
Subcutaneous injection of drug solution is
widely used for continuous and low dose drug treatment. Although the drug
injections have been administered for a long time, challenges in the design of
injection devices are still needed to minimize the variability, pain, or skin
disorder by repeated drug injections. To avoid these adverse effects,
systematic study on the effects of injection conditions should be conducted to
improve the predictability of drug effect. Here, the effects of injection
conditions on the drug diffusion in tissues were investigated using X-ray
imaging techniq...
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